Medical education Microscopy Monosodium urate crystalsc.
![synovial fluid image synovial fluid image](https://gaa-science.com/wp-content/uploads/2020/09/13544766612234.jpg)
This study suggests that there is room for improvement regarding crystal identification of particularly CPP and other non-MSU crystals even in this highly motivated group. MSU crystals were well identified, but incorrect identification of non-MSU crystals occurred frequently. Correct identification of all MSU images was achieved by 81%, correct identification of all 8 pre-defined non-MSU, CPP images, and all 22 non-MSU images as non-MSU by 68, 68, and 23%, respectively. The online test was completed by 110 participants. Different crystals can closely resemble each other morphologically. free-floating crystals can become enmeshed or hidden in fibrin. numerous artifacts are also birefringent.
#Synovial fluid image plus
The primary outcome was defined as the correct identification of all eight MSU slides plus the identification of all eight pre-defined non-MSU slides as non-MSU. The microscopic examination of synovial fluid for crystals can be difficult because. Of the 22 non-MSU slides, a subset of 8 was pre-designated that were thought to be clinically important to be identified as non-MSU. The test consisted of 30 images: 8 monosodium urate (MSU) crystals, 5 calcium pyrophosphate (CPP), 4 cholesterol, 2 depot methylprednisolone, 2 calcium oxalate, 2 rice bodies, 1 hydroxyapatite, 1 liquid lipid, 1 fibrin, 1 Charcot-Leyden, and 5 different artifacts. Rheumatologists, trainees, lab technicians, and other physicians with an interest in crystal arthritis completed an online test.
![synovial fluid image synovial fluid image](https://d3i71xaburhd42.cloudfront.net/7f3f54544f44d61fe9e40b4aa3adb4642888ed3d/2-Figure2-1.png)
![synovial fluid image synovial fluid image](https://pmj.bmj.com/content/postgradmedj/91/1071/35/F1.large.jpg)
The objective of this study was to assess current performance of crystal identification by professionals involved in examining synovial fluid in routine care. Testing a reading exercise for identification of several typical crystal such as the negatively birefringent needle-shaped crystals that are under polarized light microscopy is the gold standard for diagnosing gout.